Innate immunity as a target for acute cardioprotection
Abstract
Acute obstruction of a coronary artery causes myocardial ischaemia and if prolonged, may result in an ST-segment elevation myocardial infarction (STEMI). First-line treatment involves rapid reperfusion. However, a highly dynamic and co-ordinated inflammatory response is rapidly mounted to repair and remove the injured cells which, paradoxically, can further exacerbate myocardial injury. Furthermore, although cardiac remodelling may initially...
Paper Details
Title
Innate immunity as a target for acute cardioprotection
Published Date
Dec 21, 2018
Journal
Volume
115
Issue
7
Pages
1131 - 1142
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Notes
History