Original paper
The shear complexity of insulin‐stimulated vasodilatation
Abstract
Insulin-stimulated blood flow is critical to delivery and disposal of glucose in skeletal muscle. The vasodilatory action of insulin is mediated largely through activation of endothelial nitric oxide synthase (eNOS) by Akt phosphorylation. However, insulin also activates Ras/mitogen-activated protein kinase (MAPK) resulting in the release of the potent vasoconstrictor peptide endothelin-1 (Eringa et al. 2007). Thus, the vasoactive effects of...
Paper Details
Title
The shear complexity of insulin‐stimulated vasodilatation
Published Date
Dec 17, 2018
Journal
Volume
597
Issue
1
Pages
11 - 11
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Notes
History