Developing Gram-negative bacteria for the secretion of heterologous proteins
Abstract
Gram-negative bacteria are attractive hosts for recombinant protein production because they are fast growing, easy to manipulate, and genetically stable in large cultures. However, the utility of these microbes would expand if they also could secrete the product at commercial scales. Secretion of biotechnologically relevant proteins into the extracellular medium increases product purity from cell culture, decreases downstream processing...
Paper Details
Title
Developing Gram-negative bacteria for the secretion of heterologous proteins
Published Date
Dec 1, 2018
Journal
Volume
17
Issue
1
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