Comparative Risk of Venous Thromboembolism in Rheumatoid Arthritis Patients Receiving Tofacitinib Versus Those Receiving Tumor Necrosis Factor Inhibitors: An Observational Cohort Study

Objective To evaluate the risk of venous thromboembolism ( VTE ) in rheumatoid arthritis ( RA ) patients receiving tofacitinib versus those receiving tumor necrosis factor ( TNF ) inhibitors. Methods RA patients who were initiating treatment with tofacitinib or a TNF inhibitor and had not previously received any biologic agent or tofacitinib were identified from the Truven MarketScan database (2012–2016) or Medicare claims (parts A, B, and D)...