Review paper
Complement factor and T-cell interactions during alloimmune inflammation in transplantation
Abstract
Complement factor and T-cell signaling during an effective alloimmune response plays a key role in transplant-associated injury, which leads to the progression of chronic rejection (CR). During an alloimmune response, activated complement factors (C3a and C5a) bind to their corresponding receptors (C3aR and C5aR) on a number of lymphocytes, including T-regulatory cells (Tregs), and these cell-molecular interactions have been vital to modulate an...
Paper Details
Title
Complement factor and T-cell interactions during alloimmune inflammation in transplantation
Published Date
Dec 11, 2018
Journal
Volume
105
Issue
4
Pages
681 - 694
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