Bavachin attenuates LPS-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages

Yung Li Hung; Shu-Chi Wang; Katsuhiko Suzuki; Shih-Hua Fang; Chi Shuo Chen; Wei-Chung Cheng; Chia Cheng Su; Hsin Chih Yeh; Hung-Pin Tu; Po Len Liu; Chia-Yang Li

doi:https://doi.org/10.1016/j.phymed.2018.12.008

doi.org/10.1016/j.phymed.2018.12.008

Bavachin attenuates LPS-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages

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..., Chia-Yang Li

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Phytomedicine7.90

Volume: 59, Pages: 152785 - 152785

Published: Jun 1, 2019

Abstract

Bavachin is a natural product isolated from Psoralea corylifolia L. that has been applied as a traditional medicine in Asian countries. However, the anti-inflammatory effects of bavachin on LPS-induced inflammation and NLRP3 inflammasome activation by macrophages remain unclear.We investigated the anti-inflammatory effects of bavachin on LPS-activated murine macrophage cell line J774A.1 cells and murine peritoneal macrophages.J774A.1 cells and...

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Paper Details

Title

Bavachin attenuates LPS-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages

DOI

doi.org/10.1016/j.phymed.2018.12.008

Published Date

Jun 1, 2019

Journal

Phytomedicine

Volume

59

Pages

152785 - 152785

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