The Impact of Integrin β2 on Granulocyte/Macrophage Progenitor Proliferation
Abstract
Previously, we reported that although the HSPC frequency in bone marrow cells (BMC) was comparable between β2−/− and β2+/+ mice, transplantation of β2−/− BMC into lethally irradiated CD45.1 recipient resulted in more myeloid cell production than β2+/+ BMC. The objective of this study is to address if integrin β2 deficiency skews granulocyte/macrophage progenitor (GMP) proliferation. FACS analysis demonstrated that GMP frequency and cell number...
Paper Details
Title
The Impact of Integrin β2 on Granulocyte/Macrophage Progenitor Proliferation
Published Date
Feb 7, 2019
Journal
Volume
37
Issue
3
Pages
430 - 440
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History