Permeability Characteristics of a New Antifungal Topical Amphotericin B Formulation with γ-Cyclodextrins
Abstract
Amphotericin B is a low soluble broad-spectrum antifungal agent. Cyclodextrins can be added to amphotericin formulations to enhance both their solubility and antifungal properties. Semisolid amphotericin formulations containing gamma cyclodextrin (AGCD) were prepared and compared with two reference formulations-one of them without any solubility enhancer (A) and the other with DMSO (ADMSO). Rheological, the permeability through hairless mouse...
Paper Details
Title
Permeability Characteristics of a New Antifungal Topical Amphotericin B Formulation with γ-Cyclodextrins
Published Date
Dec 18, 2018
Journal
Volume
23
Issue
12
Pages
3349 - 3349
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