Alfred: interactive multi-sample BAM alignment statistics, feature counting and feature annotation for long- and short-read sequencing
Abstract
Harmonizing quality control (QC) of large-scale second and third-generation sequencing datasets is key for enabling downstream computational and biological analyses. We present Alfred, an efficient and versatile command-line application that computes multi-sample QC metrics in a read-group aware manner, across a wide variety of sequencing assays and technologies. In addition to standard QC metrics such as GC bias, base composition, insert size...
Paper Details
Title
Alfred: interactive multi-sample BAM alignment statistics, feature counting and feature annotation for long- and short-read sequencing
Published Date
Dec 6, 2018
Journal
Volume
35
Issue
14
Pages
2489 - 2491
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