DNA methylation processes in atherosclerotic plaque
Abstract
Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over 100 years and novel molecular level mechanisms in the pathophysiology are still continuously being discovered. Genetic polymorphisms (SNPs = single nucleotide polymorphisms) have explained about one tenth of the CVD risk, but polymorphisms fail to account for gene-environment interactions i.e. explain the dynamics of epigenome modifications in CVD....
Paper Details
Title
DNA methylation processes in atherosclerotic plaque
Published Date
Feb 1, 2019
Journal
Volume
281
Pages
168 - 179
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Notes
History