Glioma exosomes mediate the expansion and function of myeloid‐derived suppressor cells through microRNA‐29a/ Hbp1 and microRNA‐92a/ Prkar1a pathways

Myeloid‐derived suppressor cells (MDSCs) play a pivotal role in mediating the formation of an immunosuppressive environment and assisting tumors in evading the host immune response. However, the mechanism through which tumors manipulate the differentiation and function of MDSCs remains unclear. Here, we report that hypoxia‐induced glioma cells can stimulate the differentiation of functional MDSCs by transferring exosomal miR‐29a and miR‐92a to...