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Improved menstrual function in obese women with polycystic ovary syndrome after behavioural modification intervention—A randomized controlled trial

Published on Mar 1, 2019in Clinical Endocrinology 3.08
· DOI :10.1111/cen.13919
Emma Öberg (Karolinska Institutet), Sebastian Gidlöf7
Estimated H-index: 7
(Karolinska Institutet)
+ 3 AuthorsAngelica Lindén Hirschberg34
Estimated H-index: 34
(Karolinska Institutet)
  • References (33)
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References33
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Published on Sep 1, 2018in Human Reproduction 4.99
Helena Teede48
Estimated H-index: 48
(National Health and Medical Research Council),
Marie Louise Misso22
Estimated H-index: 22
(National Health and Medical Research Council)
+ 67 AuthorsRicardo Azziz65
Estimated H-index: 65
(State University of New York System)
Study Question What is the recommended assessment and management of women with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertise, and consumer preference? Summary Answer International evidence-based guidelines including 166 recommendations and practice points, addressed prioritized questions to promote consistent, evidence-based care and improve the experience and health outcomes of women with PCOS. What Is Known Already Previous guidelines either lacked ...
63 Citations Source Cite
Published on May 1, 2017in Obstetrics & Gynecology 4.98
Andrea Stuart4
Estimated H-index: 4
,
Karin Källén41
Estimated H-index: 41
OBJECTIVE:: To compare the rates of abdominal surgery during pregnancy among women with previous bariatric surgery (women in the case group) and women with first-trimester body mass index (BMI) greater than 35 and no previous bariatric surgery (women in the control group). METHODS:: We conducted a national cohort study, merging data from the Swedish Medical Birth Registry and the Swedish National Patient Registry, comparing women who had bariatric surgery from 1987 to 2011 with women in a contro...
4 Citations Source Cite
Vasileios Charalampakis4
Estimated H-index: 4
(Heart of England NHS Foundation Trust),
Abd A. Tahrani21
Estimated H-index: 21
(University of Birmingham)
+ 2 AuthorsRishi Singhal Mrcs8
Estimated H-index: 8
(Heart of England NHS Foundation Trust)
Abstract One of the most effective methods to tackle obesity and its related comorbidities is bariatric surgery. Polycystic ovary syndrome (PCOS) and endometrial hyperplasia (EH), which are associated with increased risk of endometrial carcinoma, have been identified as potentially new indications for bariatric surgery. PCOS is the most common endocrine disorder in women in the reproductive age and is associated with several components of the metabolic syndrome such as obesity, insulin resistanc...
11 Citations Source Cite
Published on Jun 4, 2015in The New England Journal of Medicine 79.26
Aaron B. Caughey57
Estimated H-index: 57
17 Citations Source Cite
Yuyong Ke8
Estimated H-index: 8
,
Renaud Gonthier8
Estimated H-index: 8
+ 4 AuthorsFernand Labrie103
Estimated H-index: 103
Abstract Quantification of steroidal glucuronide conjugates by the indirect methods of immunoassay and GC–MS/MS may underestimate some conjugates since hydrolysis is needed in sample processing. In the present work, a sensitive and rapid liquid chromatography-tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the simultaneous direct quantification of androsterone glucuronide, etiocholanolone glucuronide, and androstan-3α, 17β diol 17-glucuronide in postmenopausal wom...
20 Citations Source Cite
Published on Jan 1, 2015in Journal of Physical Therapy Science
Volkan Turan1
Estimated H-index: 1
,
Ebru Kaya Mutlu5
Estimated H-index: 5
(Istanbul University)
+ 6 AuthorsMehtap Malkoç6
Estimated H-index: 6
(Dokuz Eylül University)
[Purpose] The short-term effects of structured exercise on the anthropometric, cardiovascular, and metabolic parameters of non-overweight women diagnosed with polycystic ovary syndrome were evaluated. [Subjects and Methods] Thirty women with a diagnosis of polycystic ovary syndrome were prospectively randomized to either a control group (n=16) or a training group (n=14) for a period of 8 weeks. Anthropometric, cardiovascular, and metabolic parameters and hormone levels were measured and compared...
4 Citations Source Cite
Yuyong Ke8
Estimated H-index: 8
,
Jonathan Bertin4
Estimated H-index: 4
+ 2 AuthorsFernand Labrie103
Estimated H-index: 103
Abstract Steroids were first analyzed by immunoassay-based methods followed by gas chromatography mass spectrometry (GC–MS or GC–MS/MS) with derivatization techniques since steroids are neutral and do not ionize at a high level using the electrospray ionization technique. We now report a validated liquid chromatography tandem mass spectrometry (LC–MS/MS) method for the simultaneous quantification of seven steroidal compounds, i.e., estradiol (E 2 ), estrone (E 1 ), testosterone (Testo), dihydrot...
74 Citations Source Cite
Published on Dec 1, 2012in Endocrine Reviews 15.54
Evanthia Diamanti-Kandarakis48
Estimated H-index: 48
(National and Kapodistrian University of Athens),
Andrea Dunaif56
Estimated H-index: 56
(Northwestern University)
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected women have marked insulin resistance, independent of obesity. This article summarizes the state of the science since we last reviewed the field in the Endocrine Reviews in 1997. There is general agreement that obese women with PCOS are insulin resistant, but some groups of lean affected women may have normal insulin se...
502 Citations Source Cite
Published on Dec 1, 2011in Fertility and Sterility 4.80
Åsa Nybacka4
Estimated H-index: 4
(Karolinska University Hospital),
Kjell Carlström43
Estimated H-index: 43
(Karolinska University Hospital)
+ 3 AuthorsAngelica Lindén Hirschberg34
Estimated H-index: 34
(Karolinska University Hospital)
Objective To compare the influence of dietary management and/or physical exercise on ovarian function and metabolic variables in women with polycystic ovary syndrome (PCOS). Design Randomized 4-month trial with three interventions and a long-term follow-up. Setting Women's health clinical research unit at a university hospital. Patient(s) Fifty-seven overweight/obese women with PCOS. Intervention(s) Dietary management, physical exercise, or both, using programs individually adapted and supervise...
62 Citations Source Cite
Elizabeth Jedel7
Estimated H-index: 7
,
Fernand Labrie103
Estimated H-index: 103
+ 6 AuthorsElisabet Stener-Victorin43
Estimated H-index: 43
Background: Polycystic ovary syndrome (PCOS), the most common endocrine disorder in women of reproductive age, is characterized by hyperandrogenism, oligo/amenorrhea, and polycystic ovaries. We aimed to determine whether low-frequency electro-acupuncture (EA) decreases hyperandrogenism and improves oligo/amenorrhea more effectively than physical exercise or no intervention. Methods: We randomized 84 women with PCOS, aged 18-37 years, to 16 weeks of low-frequency EA, physical exercise, or no inte...
102 Citations Source Cite
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