A Covalent Inhibitor for Glutathione S ‐Transferase Pi (GSTP 1‐1 ) in Human Cells

Volume: 20, Issue: 7, Pages: 900 - 905
Published: Feb 15, 2019
Abstract
Glutathione S-transferase π (GSTP1-1 ) is overexpressed in many types of cancer and is involved in drug resistance. Therefore, GSTP1-1 is an important target in cancer therapy, and many GST inhibitors have been reported. We had previously developed an irreversible inhibitor, GS-ESF, as an effective GST inhibitor; however, its cellular permeability was too low for it to be used in inhibiting intracellular GST. We have now developed new...
Paper Details
Title
A Covalent Inhibitor for Glutathione S ‐Transferase Pi (GSTP 1‐1 ) in Human Cells
Published Date
Feb 15, 2019
Volume
20
Issue
7
Pages
900 - 905
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.