Anticancer effects of anti-CD47 immunotherapy in vivo
Abstract
The treatment of breast cancer largely depends on the utilization of immunogenic chemotherapeutics, which, as a common leitmotif, stimulate the exposure of calreticulin (CALR) on the surface of cancer cells, thereby facilitating their recognition by dendritic cells for the uptake of tumor-associated antigens and subsequent antigen cross-presentation to cytotoxic T cells. Breast cancer cells also express the calreticulin antagonist CD47, which...
Paper Details
Title
Anticancer effects of anti-CD47 immunotherapy in vivo
Published Date
Dec 11, 2018
Journal
Volume
8
Issue
3
Pages
1550619 - 1550619
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