Effects of aspirin for primary prevention in persons with diabetes mellitus: the ASCEND Study Collaborative Group

Multicenter prospective randomized trial from 2005 to 2011 as part of A Study of Cardiovascular Events in Diabetes (ASCEND) trial. A total of 15,480 men and women at least 40 years of age with diabetes mellitus (DM) without evident cardiovascular (CV) disease were randomized to 100 mg of aspirin (ASA) vs placebo daily. During a mean follow-up of 7.4 years, serious vascular events occurred in significantly fewer patients taking ASA (8.5%) than...