Biomarkers in colorectal cancer: Current clinical utility and future perspectives
Abstract
Colorectal cancer (CRC) is a major cause of cancer death worldwide. CRC has poor prognosis and there is a crucial need for new diagnostic and prognostic biomarkers to avoid CRC-related deaths. CRC can be considered a sporadic disease in most cases (75%-80%), but it has been suggested that crosstalk between gene mutations (i.e., mutations of BRAF, KRAS, and p53 as well as microsatellite instability) and epigenetic alterations (i.e., DNA...
Paper Details
Title
Biomarkers in colorectal cancer: Current clinical utility and future perspectives
Published Date
Dec 6, 2018
Volume
6
Issue
15
Pages
869 - 881
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