Review paper
Proteomic analysis of protein homeostasis and aggregation
Abstract
Protein homeostasis (proteostasis) refers to the ability of cells to preserve the correct balance between protein synthesis, folding and degradation. Proteostasis is essential for optimal cell growth and survival under stressful conditions. Various extracellular and intracellular stresses including heat shock, oxidative stress, proteasome malfunction, mutations and aging-related modifications can result in disturbed proteostasis manifested by...
Paper Details
Title
Proteomic analysis of protein homeostasis and aggregation
Published Date
Apr 1, 2019
Journal
Volume
198
Pages
98 - 112
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