Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor
Abstract
Translation across species of immunoassay results is often challenging due to the lack of cross-species reactivity of antibodies. In order to investigate the biology of insulin and IGF1 receptors, we generated new versatile monoclonal assay antibodies using the extracellular domain of the insulin/IGF1 hybrid receptor as the bait protein in the Adimab yeast antibody discovery platform and as the antigen in a rabbit monoclonal antibody platform....
Paper Details
Title
Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor
Published Date
Feb 1, 2019
Volume
465
Pages
20 - 26
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