Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine
Abstract
Immune checkpoint blockade (ICB) therapies, which potentiate the body's natural immune response against tumor cells, have shown immense promise in the treatment of various cancers. Currently, tumor mutational burden (TMB) and programmed death ligand 1 (PD-L1) expression are the primary biomarkers evaluated for clinical management of cancer patients across histologies. However, the wide range of responses has demonstrated that the specific...
Paper Details
Title
Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine
Published Date
Nov 29, 2018
Journal
Volume
10
Issue
1
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