Match!

Chapter 93 – Disorders of the Thyroid Gland

Published on Jan 1, 2012in Avery's Diseases of the Newborn
· DOI :10.1016/B978-1-4377-0134-0.10093-9
Sureka Bollepalli2
Estimated H-index: 2
,
Sureka Bollepalli2
Estimated H-index: 2
,
Susan R. Rose42
Estimated H-index: 42
Abstract
  • References (88)
  • Citations (2)
📖 Papers frequently viewed together
2013
1 Author (Meena Desai)
2014
1 Author (Sara-Catrin Cook)
78% of Scinapse members use related papers. After signing in, all features are FREE.
References88
Newest
#1Kazuhiko Bessho (Osaka University)H-Index: 12
#2Yuri Etani (Osaka University)H-Index: 13
Last. Keiichi Ozono (Osaka University)H-Index: 46
view all 13 authors...
Introduction Infantile hepatic hemangioma with consumptive hypothyroidism is a rare condition.
40 CitationsSource
#1Carlo CorbettaH-Index: 13
#2Giovanna Weber (UniSR: Vita-Salute San Raffaele University)H-Index: 27
Last. Luca Persani (University of Milan)H-Index: 55
view all 9 authors...
Summary Context The guidelines of the National Academy of Clinical Biochemistry advocated the use of low bloodspot TSH (b-TSH) threshold for newborn screening of congenital hypothyroidism (CH). The impact generated by the application of this indication is largely unknown. Objective To determine the impact on CH epidemiology and classification generated by the introduction of low b-TSH cutoff. Design Retrospective study of 629,042 newborns screened with b-TSH cutoffs of 12 (years 1999–2002) or 10...
146 CitationsSource
#1Yan-Hong GuH-Index: 5
#2Shohei HaradaH-Index: 10
Last. Fumiki HiraharaH-Index: 29
view all 6 authors...
Background: Much remains unknown regarding extrathyroidal congenital malformations (ECMs) in patients with primary congenital hypothyroidism (PCH) and Down syndrome (DS). Here, we investigated the frequency of ECMs in patients with PCH, particularly among patients with or without DS. Methods: In a retrospective review of questionnaires based on medical records, ECMs were identified in 1520 patients with PCH and were compared with congenital malformations among nationwide live births or liveborn ...
12 CitationsSource
#1David CartwrightH-Index: 1
#2Paula O'SheaH-Index: 2
Last. David J. HalsallH-Index: 33
view all 13 authors...
Familial dysalbuminemic hyperthyroxinemia (FDH)1 is a well-characterized condition associated with increased circulating total thyroxine (T4) concentrations and normal physiological thyroid function. It is caused by mutations in the ALB (albumin) gene that increase the affinity of albumin for T4 by approximately 60-fold. When measured by a technique that minimally disturbs the equilibria between T4 and its serum binding proteins, such as equilibrium or symmetric dialysis (SyD) performed in a nea...
36 CitationsSource
To the Editor: Graves' disease is treated with antithyroid drugs, radioactive iodine, or surgery.1,2 Propylthiouracil and methimazole are widely used in children as first-line therapy.1,2 Over the past 60 years of propylthiouracil and methimazole use, reports of propylthiouracil-related liver failure and death have accumulated.3–5 In contrast, this problem has not been reported with methimazole use in children.3,5 Several observations can be made on the basis of the medical literature, adverse e...
79 CitationsSource
#1Isabela Leite Pezzuti (UFMG: Universidade Federal de Minas Gerais)H-Index: 7
#2Patrícia P. de Lima (UFMG: Universidade Federal de Minas Gerais)H-Index: 4
Last. Vera M. A. Dias (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
view all 3 authors...
Objective: To evaluate the clinical profile of newborns with congenital hypothyroidism identified by the Newborn Screening Program of the State of Minas Gerais, Brazil, between 2000 and 2006. Methods: Analysis of factors involved in this profile, including: TSH and FT4 levels (determined by chemiluminescence, with limits of normality set at 0.3-5.0 µUI/mL and 0.8-1.8 ng/dL, respectively), age at diagnosis and age at treatment. The study sample consisted of 443 children, 55.8% were female and 95%...
9 CitationsSource
#1Isabela Leite Pezzuti (UFMG: Universidade Federal de Minas Gerais)H-Index: 7
#2Patrícia P. de Lima (UFMG: Universidade Federal de Minas Gerais)H-Index: 4
Last. Vera M. A. Dias (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
view all 3 authors...
OBJECTIVE: To evaluate the clinical profile of newborns with congenital hypothyroidism identified by the Newborn Screening Program of the State of Minas Gerais, Brazil, between 2000 and 2006. METHODS: Analysis of factors involved in this profile, including: TSH and FT4 levels (determined by chemiluminescence, with limits of normality set at 0.3-5.0 µUI/mL and 0.8-1.8 ng/dL, respectively), age at diagnosis and age at treatment. The study sample consisted of 443 children, 55.8% were female and 95%...
10 CitationsSource
#1Peter Lauberg (AAU: Aalborg University)H-Index: 67
#2Claire BournaudH-Index: 20
Last. Jacques Orgiazzi (University of Lyon)H-Index: 22
view all 4 authors...
Graves’ disease is a common autoimmune disorder in women in fertile ages. The hyperthyroidism is caused by generation of TSH-receptor activating antibodies. In pregnancy both the antibodies and the antithyroid medication given to the mother pass the placenta and affect the foetal thyroid gland. Thyroid function should be controlled not only in the mother with Graves’ hyperthyroidism but also in her foetus. The review includes two cases illustrating some of the problems in managing Graves’ diseas...
103 CitationsSource
#1Peter Kopp (NU: Northwestern University)H-Index: 42
#2Liuska Pesce (NU: Northwestern University)H-Index: 16
Last. Juan Carlos Solis-S (NU: Northwestern University)H-Index: 2
view all 3 authors...
Pendred syndrome is an autosomal recessive disorder characterized by sensorineural hearing impairment, presence of goiter, and a partial defect in iodide organification, which may be associated with insufficient thyroid hormone synthesis. Goiter development and development of hypothyroidism are variable and depend on nutritional iodide intake. Pendred syndrome is caused by biallelic mutations in the SLC26A4 gene, which encodes pendrin, a transporter of chloride, bicarbonate and iodide. This revi...
93 CitationsSource
Fetal and neonatal thyrotoxicosis from maternal Graves disease is a very rare entity. Fetal symptoms result from the transplacental passage of thyroid-stimulating immunoglobulins, which persist in the neonate resulting in neonatal symptoms. We present a case of fetal and neonatal thyrotoxicosis from maternal Graves disease. Fetal symptoms were controlled with maternal administration of antithyroid drugs leading to fetal thyroid inhibition. We present this case with a brief review of the literatu...
8 CitationsSource
Cited By2
Newest
Late-onset circulatory collapse (LCC) is a refractory hypotension occurring after the early neonatal period (>day 7), in very low-birthweight infants. Typically, infants stabilized within the early neonatal period develop sudden onset of circulatory collapse after the early neonatal period. The underlying pathophysiology of LCC is considered to be relative adrenal insufficiency, which is well known in Japan, but is not widely accepted in North America or Europe. The current increase in LCC in Ja...
8 CitationsSource
#1A Yamamoto (Kyoto University)H-Index: 1
#2Masahiko Kawai (Kyoto University)H-Index: 19
Last. Toshio Heike (Kyoto University)H-Index: 43
view all 7 authors...
Response to thyrotropin-releasing hormone stimulation tests in preterm infants with transient hypothyroxinemia of prematurity
5 CitationsSource