New Advances in Adaptive Thermogenesis: UCP1 and Beyond
Abstract
Brown and beige adipocytes can catabolize stored energy to generate heat, and this distinct capacity for thermogenesis could be leveraged as a therapy for metabolic diseases like obesity and type 2 diabetes. Thermogenic adipocytes drive heat production through close coordination of substrate supply with the mitochondrial oxidative machinery and effectors that control the rate of substrate oxidation. Together, this apparatus affords these...
Paper Details
Title
New Advances in Adaptive Thermogenesis: UCP1 and Beyond
Published Date
Jan 8, 2019
Journal
Volume
29
Issue
1
Pages
27 - 37
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