Insulin Reduces Reaction of Follicular Granulosa Cells to FSH Stimulation in Women With Obesity-Related Infertility During IVF

Women with obesity usually need larger doses of FSH for ovarian stimulation, resulting in poor outcomes; however, the mechanism is still unclear.To investigate the molecular regulation of FSH receptor (FSHR) expression associated with obesity.Case-control study to improve in vitro fertilization (IVF) outcomes.Women with obesity (82) and women who were overweight (457) undergoing IVF and 1790 age-matched controls with normal weight from our...