THE EFFECT OF MESENCHYMAL STEM CELL DERIVED MICROVESICLES IN REPAIR OF FEMORAL CHONDRAL DEFECTS IN DOGS

Mesenchymal stem cells (MSCs) releases in culture extracellular vesicles called microvesicles (MVs). MVs have beneficial cytokines that prevent progression of the disease and help in the regeneration process. This study is aimed to evaluate the effect of MSCs derived MVs in repair of induced chondral defect in a dog model. Methods: Chondral defects were created surgically ([Formula: see text][Formula: see text]mm) in both femoral condyles of...