Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria
Abstract
Bacteria and mitochondria contain translocases that function to transport proteins across or insert proteins into their inner and outer membranes. Extant mitochondria retain some bacterial-derived translocases but have lost others. While BamA and YidC were integrated into general mitochondrial protein transport pathways (as Sam50 and Oxa1), the inner membrane TAT translocase, which uniquely transports folded proteins across the membrane, was...
Paper Details
Title
Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria
Published Date
Nov 22, 2018
Journal
Volume
16
Issue
1
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