Immunophysical Evaluation of the Initiating Step in the Formation of the Membrane Attack Complex
Abstract
The complex between complement system proteins C5b and C6 is the cornerstone for the assembly of the membrane attack complex (MAC, also known as C5b6789n). MAC is the terminal product of three converging pathways of the complement system and functions as a pore forming complex on cell surfaces, as a response of the immune system in fighting pathogens. However, when proper regulation of the complement system is compromised, MAC also attacks host...
Paper Details
Title
Immunophysical Evaluation of the Initiating Step in the Formation of the Membrane Attack Complex
Published Date
Nov 20, 2018
Journal
Volume
6
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