Proinflammatory Effects of Calprotectin in Graves’ Orbitopathy
Abstract
Purpose: Early detection and control of inflammation are important to manage Graves’ orbitopathy (GO). We investigated the effects of calprotectin (S100A8/A9) on orbital fibroblast inflammation and GO pathogenesis.Methods: We measured serum calprotectin, S100A8 and S100A9 mRNA expression in orbital fat/connective tissue from GO patients and healthy controls, and proinflammatory cytokines in primary cultured orbital fibroblasts.Results: The serum...
Paper Details
Title
Proinflammatory Effects of Calprotectin in Graves’ Orbitopathy
Published Date
Nov 19, 2018
Volume
28
Issue
1
Pages
156 - 163
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