Disentangling tobacco-related lung cancer—genome-wide interaction study of smoking behavior and non-small cell lung cancer risk

Lung cancer poses a serious health problem worldwide being the first cancer in incidence and the leading cause of cancer death in developed countries (1). According to its histological characteristics lung cancer is subdivided into two types; the main one is non-small cell lung cancer (NSCLC) which originates from bronchial epithelial-cell precursors and small cell lung cancer (SCLC) that originates in neuroendocrine cells. NSCLC is the most...