Honey bee Royalactin unlocks conserved pluripotency pathway in mammals
Abstract
Royal jelly is the queen-maker for the honey bee Apis mellifera, and has cross-species effects on longevity, fertility, and regeneration in mammals. Despite this knowledge, how royal jelly or its components exert their myriad effects has remained poorly understood. Using mouse embryonic stem cells as a platform, here we report that through its major protein component Royalactin, royal jelly can maintain pluripotency by activating a ground-state...
Paper Details
Title
Honey bee Royalactin unlocks conserved pluripotency pathway in mammals
Published Date
Dec 4, 2018
Journal
Volume
9
Issue
1
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