Transglutaminase 1 Replacement Therapy Successfully Mitigates the Autosomal Recessive Congenital Ichthyosis Phenotype in Full-Thickness Skin Disease Equivalents
Volume: 139, Issue: 5, Pages: 1191 - 1195
Published: May 1, 2019
Abstract
Autosomal recessive congenital ichthyosis (ARCI) disrupts normal keratinization, resulting in generalized scaling of the skin. There are presently no curative therapies available (Fleckman et al., 2013Fleckman P. Newell B.D. Van Steensel M.A. Yan A.C. Topical treatment of ichthyoses.Dermatol Ther. 2013; 26: 16-25Crossref PubMed Scopus (15) Google Scholar). Local protein replacement is, therefore, an encouraging approach for a more specific...
Paper Details
Title
Transglutaminase 1 Replacement Therapy Successfully Mitigates the Autosomal Recessive Congenital Ichthyosis Phenotype in Full-Thickness Skin Disease Equivalents
Published Date
May 1, 2019
Volume
139
Issue
5
Pages
1191 - 1195
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