Robust desynchronization of Parkinson’s disease pathological oscillations by frequency modulation of delayed feedback deep brain stimulation

Volume: 13, Issue: 11, Pages: e0207761 - e0207761
Published: Nov 20, 2018
Abstract
The hyperkinetic symptoms of Parkinson’s Disease (PD) are associated with the ensembles of interacting oscillators that cause excess or abnormal synchronous behavior within the Basal Ganglia (BG) circuitry. Delayed feedback stimulation is a closed loop technique shown to suppress this synchronous oscillatory activity. Deep Brain Stimulation (DBS) via delayed feedback is known to destabilize the complex intermittent synchronous states....
Paper Details
Title
Robust desynchronization of Parkinson’s disease pathological oscillations by frequency modulation of delayed feedback deep brain stimulation
Published Date
Nov 20, 2018
Journal
Volume
13
Issue
11
Pages
e0207761 - e0207761
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