Analysing single-molecule trajectories to reconstruct free-energy landscapes of cyclic motor proteins
Abstract
Stochastic trajectories measured in single-molecule experiments have provided key insights into the microscopic behaviour of cyclic motor proteins. However, the fundamental free-energy landscapes of motor proteins are currently only able to be determined by computationally intensive numerical methods that do not take advantage of available single-trajectory data. In this paper we present a robust method for analysing single-molecule trajectories...
Paper Details
Title
Analysing single-molecule trajectories to reconstruct free-energy landscapes of cyclic motor proteins
Published Date
Feb 1, 2019
Volume
462
Pages
321 - 328
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