Review paper
The molecular origins and pathophysiological consequences of micronuclei: New insights into an age-old problem
Abstract
Micronuclei (MN), the small nucleus-like bodies separated from the primary nucleus, can exist in cells with numerical and/or structural chromosomal aberrations in apparently normal tissues and more so in tumors in humans. While MN have been observed for over 100 years, they were merely and constantly considered as passive indicators of chromosome instability (CIN) for a long time. Relatively little is known about the molecular origins and...
Paper Details
Title
The molecular origins and pathophysiological consequences of micronuclei: New insights into an age-old problem
Published Date
Jan 1, 2019
Volume
779
Pages
1 - 35
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