Physiological and Perceived Exertion Responses during Exercise: Effect of β-blockade

Purpose This study investigated the effect of β-blockade on physiological and perceived exertion (RPE) responses during incremental treadmill exercise. Methods Sixteen healthy participants ( n = 8 men; age, 25.3 ± 4.6 yr) performed a maximal treadmill exercise test after ingestion of 100 mg metoprolol or placebo, with a double-blind, randomized, and counterbalanced design. Heart rate (HR), ventilatory, and gas exchange variables were measured...