Effects of ZnO nanoparticles on intestinal function and structure in normal/high fat diet-fed rats and Caco-2 cells

Aim: The present study was carried out to determine the effects of ZnO nanoparticles (ZnO–NPs) on intestinal function and pathophysiological alteration. Materials & methods: ZnO–NPs were synthesized and their characterizations were performed using various techniques. The Wistar male rats fed with normal diet and/or high fat diet (HFD) for 8 weeks and then orally received ZnO–NPs (5, 50 and 100 mg/kg bodyweight) for 28 days. The oxidative...