von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice
Abstract
Abdominal aortic aneurysm (AAA) refers to a localized dilation of the abdominal aorta that exceeds the normal diameter by 50%. AAA pathophysiology is characterized by progressive inflammation, vessel wall destabilization and thrombus formation. Our aim was to investigate the potential involvement of von Willebrand factor (VWF), a thrombo-inflammatory plasma protein, in AAA pathophysiology using a dissection-based and angiotensin II...
Paper Details
Title
von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice
Published Date
Nov 9, 2018
Journal
Volume
8
Issue
1
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