Caloric restriction and cellular senescence
Abstract
Cellular senescence is a state of irreversible growth arrest characterized by hypertrophy and secretion of various bioactive molecules, a phenomenon defined the Senescence-Associated Secretory Phenotype (SASP). Senescent cells are implicated in a number of biological functions, from embryogenesis to aging. Significantly, excessive accumulation of senescent cells is associated to a decline of regenerative capacity and chronic inflammation. In...
Paper Details
Title
Caloric restriction and cellular senescence
Published Date
Dec 1, 2018
Volume
176
Pages
19 - 23
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