Imaging as a surrogate marker of drug efficacy in cardiovascular disease

Heart5.70
Volume: 105, Issue: 7, Pages: 567 - 578
Published: Oct 31, 2018
Abstract
### Learning objectives Many cardiovascular drugs in the pipeline will fail to demonstrate a clear clinical benefit when evaluated in large-scale clinical outcome trials, which are costly, require lengthy follow-up and can potentially expose patients to unforeseen risks. There exists an enormous gap between early mechanistic studies demonstrating proof-of-principle drug efficacy in preclinical models and successful translation of these...
Paper Details
Title
Imaging as a surrogate marker of drug efficacy in cardiovascular disease
Published Date
Oct 31, 2018
Journal
Volume
105
Issue
7
Pages
567 - 578
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