QTL Mapping on a Background of Variance Heterogeneity
Abstract
Standard QTL mapping procedures seek to identify genetic loci affecting the phenotypic mean while assuming that all individuals have the same residual variance. But when the residual variance differs systematically between groups, perhaps due to a genetic or environmental factor, such standard procedures can falter: in testing for QTL associations, they attribute too much weight to observations that are noisy and too little to those that are...
Paper Details
Title
QTL Mapping on a Background of Variance Heterogeneity
Published Date
Dec 1, 2018
Journal
Volume
8
Issue
12
Pages
3767 - 3782
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