MALAT1/miR-144/Brg1: A potential regulated axis of inflammation in myocardial ischemia-reperfusion injury

Zhang et al. recently reported that ablation of brahma related gene 1 (Brg1) in the endothelium suppressed neutrophil infiltration and down-regulated the levels of pro-inflammatory mediators in the heart following ischemia-reperfusion (IR) injury [ [1] Zhang X. Liu S. Weng X. Zeng S. Yu L. Guo J. et al. Brg1 deficiency in vascular endothelial cells blocks neutrophil recruitment and ameliorates cardiac ischemia-reperfusion injury in mice. Int. J....