Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells

Volume: 13, Issue: 10, Pages: e0206256 - e0206256
Published: Oct 31, 2018
Abstract
Recent findings point to a role of Checkpoint Inhibitor (CPI) receptors at the tissue level in immune homeostasis. Here we investigated the role of CPI molecules on immune cells in relation to cardiac function. Participants recruited in Chennai, India consisted of HIV+ ART naive viremic (Gp1 n = 102), HIV+ on ART, virologically suppressed (Gp2, n = 172) and HIV negative healthy controls (Gp3, n = 64). A cross-sectional analysis of cardiac...
Paper Details
Title
Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells
Published Date
Oct 31, 2018
Journal
Volume
13
Issue
10
Pages
e0206256 - e0206256
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