Aldehyde dehydrogenase in regulatory T‐cell development, immunity and cancer
Abstract
The role of aldehyde dehydrogenase (ALDH) in carcinogenesis and resistance to cancer therapies is well known. Mounting evidence also suggests a potentially important role for ALDH in the induction and function of regulatory T (Treg) cells. Treg cells are important cells of the immune system involved in promoting immune tolerance and preventing aberrant immune responses to beneficial or non-harmful antigens. However, Treg cells also impair tumor...
Paper Details
Title
Aldehyde dehydrogenase in regulatory T‐cell development, immunity and cancer
Published Date
Nov 22, 2018
Journal
Volume
156
Issue
1
Pages
47 - 55
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