Functional fluorescence assay of botulinum neurotoxin A in complex matrices using magnetic beads
Abstract
The extremely toxic botulinum neurotoxin poses a threat for health and food safety, requiring rapid and easy-to-use detection platforms. To meet these requirements, we have explored a novel functional assay format for detection of botulinum neurotoxin serotype A light chain (BoNT/A LC) in complex matrices. The proposed assay utilizes a synthetic peptide designed to mimic the SNAP-25 protein (synaptosomal-associated protein 25) as substrate bound...
Paper Details
Title
Functional fluorescence assay of botulinum neurotoxin A in complex matrices using magnetic beads
Published Date
Feb 1, 2019
Volume
281
Pages
912 - 919
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