Shared heritability and functional enrichment across six solid cancers
Abstract
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of European ancestry, here we estimate the pair-wise genetic correlations between breast, colorectal, head/neck, lung, ovary and prostate cancer, and between cancers and 38 other...
Paper Details
Title
Shared heritability and functional enrichment across six solid cancers
Published Date
Jan 25, 2019
Journal
Volume
10
Issue
1
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