Cyanobufalins: Cardioactive Toxins from Cyanobacterial Blooms
Abstract
Cyanobufalins A-C (1-3), a new series of cardiotoxic steroids, have been discovered from cyanobacterial blooms in Buckeye Lake and Grand Lake St. Marys in Ohio. Compounds 1-3 contain distinctive structural features, including geminal methyl groups at C-4, a 7,8 double bond, and a C-16 chlorine substituent that distinguish them from plant- or animal-derived congeners. Despite these structural differences, the compounds are qualitatively identical...
Paper Details
Title
Cyanobufalins: Cardioactive Toxins from Cyanobacterial Blooms
Published Date
Oct 28, 2018
Journal
Volume
81
Issue
11
Pages
2576 - 2581
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