Systemic immunoglobulin light chain amyloidosis
Abstract
Systemic immunoglobulin light chain amyloidosis is a protein misfolding disease caused by the conversion of immunoglobulin light chains from their soluble functional states into highly organized amyloid fibrillar aggregates that lead to organ dysfunction. The disease is progressive and, accordingly, early diagnosis is vital to prevent irreversible organ damage, of which cardiac damage and renal damage predominate. The development of novel...
Paper Details
Title
Systemic immunoglobulin light chain amyloidosis
Published Date
Oct 25, 2018
Volume
4
Issue
1
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