Chemiluminescence-triggered fluorophore release: Approach for in vivo fluorescence imaging of hydrogen peroxide

Chemiluminescence (CL) of luminol is a well-established technology for in vitro biochemical analysis of hydrogen peroxide (H2O2). However, applications of chemiluminescence as a signal transduction trigger for fluorophore release still remain to be exploited. In this paper, we rationally design a chemiluminescence-triggered fluorophore release approach for imaging of H2O2 in vivo. The o-benzyl alcohol-decorated block poly(carbonate)s copolymer,...