Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing
Abstract
Plasminogen (Plg) and thrombomodulin (TM) are glycoproteins well known for fibrinolytic and anticoagulant functions, respectively. Both Plg and TM are essential for wound healing. However, their significance during the reparative process was separately demonstrated in previous studies. Here, we investigate the interaction between Plg and epithelial TM and its effect on wound healing. Characterization of the wound margin revealed that Plg and TM...
Paper Details
Title
Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing
Published Date
Oct 19, 2018
Volume
96
Issue
12
Pages
1333 - 1344
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