Galectin-3 Regulates γ-Herpesvirus Specific CD8 T Cell Immunity

Volume: 9, Pages: 101 - 119
Published: Nov 1, 2018
Abstract
•A comprehensive transcriptomic analysis on γ-HV-expanded TN cells was performed•CD8 T cells upregulated Gal-3 that migrated intracellularly toward immune synapse•Stimulated naive and memory cells displayed galectin-3 recruitment to immune synapse•γ−HV-infected Gal-3 KO mice mounted better CD8+ T cells and controlled virus better To gain insights into the molecular mechanisms and pathways involved in the activation of γ-herpesvirus...
Paper Details
Title
Galectin-3 Regulates γ-Herpesvirus Specific CD8 T Cell Immunity
Published Date
Nov 1, 2018
Journal
Volume
9
Pages
101 - 119
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