The anti-psychotic drug pimozide is a novel chemotherapeutic for breast cancer

Volume: 9, Issue: 79, Pages: 34889 - 34910
Published: Oct 9, 2018
Abstract
Pimozide, an antipsychotic drug of the diphenylbutylpiperidine class, has been shown to suppress cell growth of breast cancer cells in vitro. In this study we further explore the inhibitory effects of this molecule in cancer cells. We found that Pimozide inhibited cell proliferation in a dose- and time-dependent manner in MDA-MB-231 breast cancer cells and A549 lung cancer cells. Furthermore, we found that Pimozide also promoted apoptosis as...
Paper Details
Title
The anti-psychotic drug pimozide is a novel chemotherapeutic for breast cancer
Published Date
Oct 9, 2018
Journal
Volume
9
Issue
79
Pages
34889 - 34910
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