Joint X-ray/NMR structure refinement of multidomain/multisubunit systems
Abstract
Data integration in structural biology has become a paradigm for the characterization of biomolecular systems, and it is now accepted that combining different techniques can fill the gaps in each other's blind spots. In this frame, one of the combinations, which we have implemented in REFMAC-NMR, is residual dipolar couplings from NMR together with experimental data from X-ray diffraction. The first are exquisitely sensitive to the local details...
Paper Details
Title
Joint X-ray/NMR structure refinement of multidomain/multisubunit systems
Published Date
Oct 11, 2018
Journal
Volume
73
Issue
6-7
Pages
265 - 278
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